Fetal origins of adult diseases

in utero

  1. David Barker made a landmark observation of an odd correlation between low birth weights and increased rates of heart disease in middle aged individuals Barker et al., 2010.
  1. We now know that adverse exposures to fetus and infants has long term effect on health and can increase susceptibility to various diseases such as CVDs, diabetes, kidney disease and different types of cancer.
  1. A growing fetus shares the environment (exposures) that the pregnant mother encounters such as food, drink, environmental and chemical pollutants and even her emotional wellbeing. Maternal malnutrition may disrupt the development of the fetus neurons and other organs and this has been demonstrated to have long term adverse health effect over the life span of an individual.
  1. Must encourage good nutrition, avoidance of toxic environment, less stress and prenatal checkups for pregnant women, in particular minority population.
  1. Let’s cherish our pregnant women!!!!!